Inverse tissue mechanics of cell monolayer expansion

Inverse tissue mechanics of cell monolayer expansion

Living tissues undergo deformation during morphogenesis. In this process, cells generate mechanical forces that drive the coordinated cell motion and shape changes. Recent advances in experimental and theoretical techniques have enabled in situ measurement of the mechanical forces, but the characterization of mechanical properties that determine how these forces quantitatively affect tissue def...

Damage Assessment using an Inverse Fracture Mechanics approach

This paper studies the application of an inverse methodology for problem solving in fracture mechanics using the finite element analysis. The method was applied to both detection of subsurface cracks and the study of propagating cracks. The procedure for detection of subsurface cracks uses a first order optimization analysis coupled with a penalty function to solve for the unknown geometric par...

Propagation of goat pox virus on monolayer cell cultures

Statistical Mechanics of Inverse Halftoning

For many years, researchers have investigated information science, such as image analysis (Besag, 1974, Winkler, 1995, Cressie, 1993). Especially, image restoration has been studied as a fundamental problem in information science. In a recent development of this field, theoretical physicists have applied statistical mechanics to information based on analogy between statistical mechanics and Bay...

Cell and tissue mechanics: the new cell biology frontier